The use of PRA technology should be increased in all regulatory matters to the extent supported by the state of the art in PRA methods and data and in a manner that complements the NRC's deterministic approach and supports the NRC's traditional defense-in-depth philosophy.
PRA and associated analyses (e.g., sensitivity studies, uncertainty analyses, and importance measures) should be used in regulatory matters, where practical within the bounds of the state of the art, to reduce unnecessary conservatism associated with current regulatory requirements, regulatory guides, license commitments, and staff practices.
NRC - REGULATORY GUIDE 1.177
An Approach for Plant-Apecific, Risk-Informed Decisionmaking: Technical Specifications